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Kyoto Encyclopedia of Genes and Genomes (KEGG) and Gene Ontology (GO) enrichment analysis was conducted using the R ClusterProfiler package to investigate the roles of DEGs

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For example, IL-2 treatment has been shown to increase Treg numbers and reduce inflammation in COPD models (123)

12 Conversely, non-RBD-PD may reflect a brain-first subtype, in which pathological -synuclein originates within the central nervous system and then spreads peripherally