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The effects of two different doses of PXN (PXN LOW, PXN HIGH), CAF (CAF HIGH), and a control group on cognition (escape latency in the Morris water maze test), neurotransmitters (acetylcholine, dopamine, and gamma-aminobutyric acid), and neurochemicals (BDNF, catalase, glutathione, and cyclic GMP) were analyzed from whole brain samples in young (8 weeks old) and aged (16 months old) rats

Scientific Backing: Decades of research provide robust evidence of efficacy

Ziajahromi S, Neale PA, Rintoul L, Leusch FDL (2017) Wastewater treatment plants as a pathway for microplastics: Development of a new approach to sample wastewater-based microplastics

Conclusion Although UPS-mediated protein degradation has been well-studied in the last few decades, regulation of ubiquitination and proteasomal degradation in normal brain function and pathogenesis of neurodegenerative diseases remains largely unknown

H.StoflethJ