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161 Consistently, in our previous study, we provided direct evidence for Mtb targeting the host ubiquitin system by showing that Mtb PtpA directly binds to the RING domain of a host E3 ubiquitin ligase, tripartite motif containing 27 (TRIM27), to antagonize TRIM27-promoted inflammatory immune responses and cell apoptosis

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Peptides reconstituted for repeated use over several weeks are typically mixed with bacteriostatic water, since its benzyl alcohol preservative is what allows the same vial to be used safely multiple times