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As a result, cancer cells have devised strategies to protect themselves from intrinsic oxidative stress and have developed a sophisticated adaptation strategy that involves effective reorganization of antioxidant functions and allows the up-regulation of pro-survival molecules [24]

Mol Cancer Res 9: 10541066 Nikiforov MA, Chandriani S, O'Connell B, Petrenko O, Kotenko I, Beavis A, Sedivy JM, Cole MD (2002) A functional screen for Mycresponsive genes reveals serine hydroxymethyltransferase, a major source of the onecarbon unit for cell metabolism