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Furthermore, in line with the beneficial effects of RAS blockers, researchers have also shown that the administration of empagliflozin, a SGLT2i, reduced the expression of IL-6, CCL2, and NF-B in the kidneys of diabetic Akita mice, as well as in cultured kidney tubular cells exposed to high glucose (152, 159)

doi:10.1016/j.yrtph.2020.104665 Chang CH, Tsai WC, Lin MS, Hsu YH, Pang JHS

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Neurotrophic pathways: BDNF, NGF, HGF and molecular logic Most modern cognitive peptides converge on three main trophic pathways: BDNF / TrkB BDNF is the most studied trophic molecule in adult neuroplasticity

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