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Cassina et al., Role of glial cells in metabolism and ALS Although ALS is mainly characterized by the selective loss of motor neurons, neighboring non-neuronal cells such as astrocytes (Clement et al., 2007), microglia (Beers et al., 2008

Tumor cells originating from non-autophagous cells often exhibit aneuploidy, heightened oxidative stress, and DNA damage as a result of the buildup of abnormal mitochondria due to the lack of mitophagy [71]

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