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56 SunRZLeiLChengLJinZFZuSJShanZYet al

Chronic pulmonary obstruction disease (COPD), one of the causes of PH, belongs to the third PH group

Conversely, although the medium containing Met was able to enhance the percentage of culture bovine oocytes developing into viable blastocysts, the global methylation was not altered by Met concentration ( While the maternal effects of RPM on embryonic development are well understood, the dietary paternal effects on sperm functionality and reproductive performance need further evaluation

doi: 10.1186/s12864-019-6190-3 192 CostaDLNamasivayamSAmaralEPAroraKChaoAMitterederLRet al

Second, delivery systems can achieve spatiotemporal control of the treatment if they are responsive to stimuli such as pH, temperature, or light, thus keeping the cargo inactivated until it accumulates in the target cell (120, 121)