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4 From eNOS uncoupling to hypertension: several molecular mechanisms contribute to the pathology establishment The altered NO production may be involved in the essential hypertension pathogenesis, as human studies showed that an increase in the mean diurnal BP corresponded with a reduced urinary excretion of nitrate, an index of endogenous NO generation

In vitro lste NaBPC157, verabreicht in der gleichen Dosis (100 M) wie L-Arginin, in der Magenschleimhaut aus Ratten-Magengewebshomogenaten eine vergleichbare Bildung von NO aus

These discrepancies highlight the importance of considering disease phase (relapsing or progressive), clinical subtype (RRMS, PPMS, SPMS), and activation status when interpreting T cell metabolism in MS

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