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10.1016/s0928-4257(99)00124-2 [DOI] [PubMed] [Google Scholar] Sikiric P., Marovic A., Matoz W., Anic T., Buljat G., Mikus D., et al

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In the SK-N-BE cells, DOR desensitization is reduced when arrestin 2 expression is inhibited by shRNA only upon DPDPE and deltorphin I exposure but not with etorphine (Aguila et al., All those data indicate that different mechanisms are responsible for OR desensitization: some are arrestin-dependent and requires GRK while others are arrestin-independent