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They can interfere with the signals or blood supply that make cancers grow or block the DNA repair in cancer cells

ACS Biomater Sci Eng (2022) 8:364458

NMN and NR may be favourable precursors for increasing the level of NAD+ and activating the activity of the NAD+-dependent enzyme, sirtuins. (10) Figure adapted from: It takes two to tango: NAD+ and sirtuins in aging/longevity control NMN and NR Boost NAD+ Without Side Effects Surprisingly, there are very few studies directly comparing NAD+ precursors in humans

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The difference is this: without adequate antioxidant capacity, the metabolic stress of losing 20% body weight in six months can trigger compensatory responses