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Speer et al

Current challenges and limitations in existing Parkinsons disease therapies Recently, several studies have been conducted to find novel therapeutic tools to treat or alleviate the devastating symptoms of Parkinsons disease, whether motor or non-motor [168, 169]

In fact, a study using CNS samples from EAE demonstrated that microglia with differential expression of myeloid activation marker (MHC classII, CD86+), in addition to TREM2+, progressively increase from the asymptomatic phase to the peak of EAE (144)