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Cancer cells need the energy to sustain the high rate of proliferation and the energy need further increases with the grade of malignancy (Hanahan and Weinberg, 2011)

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Additionally, cisplatin treatment reduces macrophage viability, whereas WSG from Ganoderma lucidum L

Statistical analysis All statistical analyses were conducted with IBM SPSS Statistics v22.0 (IBM Corp., Armonk, NY, USA)

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