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& DeLeve, L

445 Additionally, intracellular HSP90, which is involved in the activation of both innate and adaptive immune responses, has been implicated in autoimmune processes

Studies in mice reveal an even more worrying trend - NAD+ levels can fall by half by middle age, which lines up with the start of many age-related issues

Suwannaroj S, Lagoo A, Keisler D, McMurray RW: Antioxidants suppress mortality in the female NZB x NZW F1 mouse model of systemic lupus erythematosus (SLE)