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moreover, in the context of immunotherapy and targeted agents there is compelling translational evidence primarily from murine models and observational cohorts in other cancers that specific taxa enhance antitumour immune responses and predict checkpoint inhibitor efficacy, suggesting analogous potential in subsets of breast cancer patients, particularly those receiving immunomodulatory regimens (177)

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These vesicles encapsulate damaged organelles, misfolded proteins and other cytoplasmic components within double-membrane structures

Despite these advances and their significant therapeutic potential, the molecular mechanisms underlying the potent cytoprotective effects of BPC157 remain largely undefined, limiting its full clinical translation