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The equilibrium K d of Hs PP5 and Hs HOP binding is 5.78 1.37 M determined by Octet BLI analysis software

Cisplatin exerts a strong promoting effective via accumulation, therefore, it tends to induce nephrotoxicity and often causes renal cell damage [170]

Hydroxocobalamin is a highly bioavailable form of Vitamin B12 that is used to treat people with serious deficiencies

10.1136/jnnp.55.3.181 101 HughesJ

Restoring GSH homeostasis could therefore help counteract redox imbalance and represents a potential therapeutic or prophylactic strategy that warrants further investigation