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Description

Springer Nature, 2016

Notably, amyloid deposits in ATTR patients correlate with markers of lipid peroxidation, such as 4hydroxytrans2nonenal (HNE) adducts [35] and oxidative DNA damage indicated by 8hydroxy2deoxyguanosine (8OhdG) [34]

In peptide therapy, synthetic versions of these naturally occurring molecules are introduced to help regulate or optimize targeted systems in the body