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In diabetes, this balance is disrupted, shifting towards excessive fission and resulting in mitochondrial fragmentation and functional impairment (Sun et al., 2021)

Lack of oral GSH supplementation effects upon growth or changes in serum or fecal inflammatory markers in children with cystic fibrosis with pancreatic insufficiency (125) could be probably explained by the inability of the cells to uptake extracellular GSH to be used inside the cells