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Apixaban concentration was determined via a validated liquid chromatography with tandem mass spectrometry method with a dynamic range of 1.00200 ng/mL using 100 L of human serum:buffer performed at Alta Analytical Laboratory Inc

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Following the initial evidence on the potential antidepressant effect of melatonin, efforts have been directed toward the development of antidepressants with melatonin agonist activity