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PMID: 32649859

Lipid Handling: Glucagon receptor signaling has been associated with reductions in hepatic fat accumulation, suggesting potential benefits for conditions such as non-alcoholic fatty liver disease (NAFLD)

Targeting the epigenetic dysregulation responsible for BACE1 overexpression may mitigate the pathological drivers of A plaque formation while minimizing associated side effects

Hsieh CL, Goldsmith JA, Schaub JM, DiVenere AM, Kuo HC, Javanmardi K, et al

For example, the entry of glutamine through SLC1A5, combined with its exit through the SLC7A5/LAT1 transporter, allows leucine to enter the cell and trigger mTORC1-mediated cell growth