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Distinct proteomic and post-translational impacts of class-defining AML alterations To explore the imprint of recurrent genetic alterations on the AML proteome, we linked common genetic alterations to differences in the abundance of proteins and PTMs (Methods)

RNA seq analysis Total RNA of ankles from the saline group ( n = 3) and SP@M group ( n = 3) were extracted as per the manufacturers protocol

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This further promotes an autoamplification loop that exaggerates inflammation and cell death and leads to a more severe degree of cell death and a range of inflammation-related responses [95, 96]

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