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The critical unanswered question is whether a topical product delivers GHK-Cu to viable dermis at concentrations above these effective thresholds

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In addition to proinflammatory cytokines for cancer therapy, anti-inflammatory cytokines like IL-10 have also been incorporated onto nanoparticles to prevent excessive immune activation and to protect from tissue damage (86)

That modification, a trans-3-hexenoic acid group, makes it far more resistant to enzymatic breakdown than the GHRH your body produces on its own