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There is some evidence that high fevers during pregnancy, particularly during the first trimester, can harm the baby, with a higher risk of miscarriage, preterm birth, or birth defects called NTDs, or neural tube defects

Notably, Pan et al

For patients unable to tolerate live preparationssuch as immunocompromised or critically ill individualsor those requiring long-term, stable therapy, postbiotics offer a safe, controllable alternative

Acknowledgements The authors wish to acknowledge Humphrey Chukwudi Omeoga, of Thomas BegLey Laboratory, Department of Biological Sciences, State University of New York, at Albany, New York USA for using his licensed accessed BioRender for the diagrams sketching

Gui Z, Li J, Li J, et al