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NMDA receptor activation mediates hydrogen peroxide-induced pathophysiology in rat hippocampal slices

This is possible because, despite the traditional classification of adult CNS neurons as non-regenerative, they maintain a latent capacity for growth

Extracellular signal-regulated kinase (ERK), a MAP kinase family that modifies gene expression through the phosphorylation of a variety of transcription factors, is the most frequent pathway associated with the control of cell proliferation

Such mice are available from Abgenix, Inc., Fremont, California, and Medarex, Inc., Annandale, New Jersey