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Lipid effects of peroxisome proliferator-activated receptor- agonist GW501516 in subjects with low high-density lipoprotein cholesterol: characteristics of metabolic syndrome The objective of this study was to investigate the effects of GW501516, a peroxisome proliferator-activated receptor-delta (PPAR) agonist, on lipid and lipoprotein profiles in patients with low high-density lipoprotein (HDL) cholesterol levels

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Other studies have shown that TMEM106B knockdown or KO increases the number of moving lysosomes and retrograde transport of lysosomes in dendrites of DIV9 primary rat hippocampal neurons [146] and in axons of DIV7 primary mouse motoneurons [89]

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