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Furthermore, a recent MRS-PET study found that GSH levels in the parietal lobe were negatively correlated with A accumulation in healthy individuals 49

Ubiquitin-mediated proteasomal degradation tightly controls p53 activity at the cellular level

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However, studies have shown that isobavachalcone (IBC), a natural prenylated chalcone compound, induces mitochondria-dependent apoptosis in GBM while alleviating pyroptosis [196]