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It works especially well for those who are physically active or trying to maintain muscle while losing weight

Agorrody G, Peclat TR, Peluso G, Gonano LA, Santos L, van Schooten W, et al

A B12 drip, also called vitamin B12 intravenous (IV) therapy, is a method of delivering high doses of B12 directly into the bloodstream through an IV

Vitamin B12 is measured in micrograms (mcg) , with a standard dose of 1,000 mcg per injection

Animal experiments (in mice) have shown that pharmacologic blockade or genetic deletion of the Y1- and Y5-receptors reduces food intake and weight, with Y1-receptor signaling appearing to be the major mediator of the orexigenic effects of NPY