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Tamoxifen Tamoxifen is a nonsteroidal anti-oestrogen, believed to modulate transforming growth factor (TGF)1 by fibroblasts and thereby affecting deposition of scar tissue [21]

Qiao C, Zhang Q, Jiang Q, Zhang T, Chen M, Fan Y, Ding J, Lu M, Hu G (2018) Inhibition of the hepatic Nlrp3 protects dopaminergic neurons via attenuating systemic inflammation in a MPTP/p mouse model of Parkinsons disease

Few human or murine studies exist regarding the influence of aging on susceptibility to drug induced liver injury 35 , which is often complicated by confounding factors including polypharmacy and genetics, among others