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In a 2021 study of 182 adults with frequent migraines, researchers from the National Institutes of Health, in cooperation with other investigators, assigned participants to one of three groups for 16 weeks comparing a diet high in omega-3 fatty acids from high-fat fish and low in linoleic acid, a diet high in omega-3s but with as much linoleic acid as in the average U.S

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[DOI] [PubMed] [Google Scholar] 141.Naidu P.S., Booker L., Cravatt B.F., Lichtman A.H