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doi: 10.1182/blood-2017-10-809293 43 BuschLMougiakakosDBttner-HeroldMMllerMJVolmerDABachCet al

Methylfolate produces rapid improvement here (26 28)

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Preferential loss of abdominal fat observed, resembling the pattern seen with lowdose hGH therapy [10]

In a phase 2 dose-finding trial, once-weekly Cagrilintide produced clinically meaningful weight loss about 10.8% at the 4.5 mg dose over 26 weeks with gastrointestinal effects the most common adverse events [1]