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3.2 Mitochondrial metabolism and redox homeostasis While the glycolytic shift under hypoxia is a defining feature of tumor metabolism, alterations in mitochondrial function and redox homeostasis are equally critical to cancer cell adaptation (77)

When the sample size was sufficiently large in the species accumulation curve, the total number of species in the community would no longer significantly increase with an increase in sample size, and the curve would become flat (Figure 5B)

In support of the role of Kupffer cells in carbon-tetrachloride-induced hepatic damage, it was reported that gadolinium chloride (10 mg/kg given intravenously 24 h before carbon tetrachloride administration) prevented and methyl palmitate, another Kupffer cell inhibitor, attenuated the periportal oedema observed using proton magnetic imaging 1-2 h after carbon tetrachloride administration (0.8 ml/kg given intraperitoneally) (Towner et al., 1994)

Oliguria can be defined as urine output of less than or equal to 0