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Furthermore, the upregulated proteins had a special relationship with the ribonucleoprotein complex (ribosome), whereas the downregulated proteins were more related to the cilium (Fig

Journal of pain research, 12, 13411351

Subsequently, abnormal methionine affected the conversion of methionine into S-adenosylmethionine (SAM), a primary methyl donor for most cellular methytransferase reactions, including the methylation of DNA, RNA, proteins, phospholipids, and neurotransmitters [3]