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Importantly, PDE5 inhibitors do not increase nitric oxide production

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Diabetic peripheral neuropathic pain is a stronger predictor of depression than other diabetic complications and comorbidities

The authors gratefully acknowledge the support of the BBSRC Institute Strategic Programmes Food Innovation and Health [BB/R012512/1] and its constituent projects [BBS/E/F/000PR10343, BBS/E/F/000PR10346], Food Microbiome and Health [BB/X011054/1] and its constituent projects [BBS/E/QU/230001B, BBS/E/QU/230001D], and the BBSRC Core Capability Grant BB/CCG2260/1

However, its always a good idea to consult with a doctor before starting any new supplement regimen