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Apart from TJ disruption, increased epithelial cell death directly leads to the loss of barrier function

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Eur J Med Res 29:386 [DOI] [PMC free article] [PubMed] [Google Scholar] 149.Hachimi-Idrissi S (2023) Stem cell therapy in neurological disorders: promises and concerns

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By acting as a carrier and regulator of bioavailable copper, GHK-Cu plays a role in maintaining metal homeostasis and influencing downstream pathways linked to cellular growth, differentiation, and tissue remodelling