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The Yeast H+-ATPase Pma1 Promotes Rag/Gtr-dependent TORC1 Activation in Response to H+-coupled Nutrient Uptake

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We demonstrated using NMR that FOXO4DRI peptide competes with FOXO4 for p53 binding and therefore can efficiently interfere with the FOXO4 p53 interaction Mechanistically, FOXO4DRI promotes nuclear exclusion of active p53

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27 Competition in the distribution of 5,10-methyleneTHF between thymidylate biosynthesis and remethylation pathways indicates that common MTHFR variants (C677T and A1298C) may also alter activity of the multienzyme complex in thymidylate production during DNA repair