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NAFLD is a broad spectrum of diseases that encompasses simple fatty liver and nonalcoholic hepatitis (NASH), which can progress to cirrhosis and liver cancer

A growing body of research suggests low-dose colchicine (generally 0.5 mg per day) may reduce the risk of blood clot-related cardiovascular events such as heart attack and strokeespecially when used in conjunction with other standard cardiovascular medicationsthrough its ability to reduce inflammatory signaling in blood vessels

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A robust reversal of cysteine S-glutathionylation modifications was observed across the skeletal muscle proteome, and treated animals demonstrated significantly greater fatigue resistance, muscle mass, and treadmill endurance compared to untreated aged controls