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After consideration of public comments, we are finalizing as proposed at 427.303(b)(2)

Vitamin B12 deficiency has been linked to fatigue, tingling or loss of feeling in the extremities, irritability, memory impairment, depression, anemia, irritable bowel syndrome (IBS), constipation, poor wound healing, dry or damaged looking skin, and neurological disorders

10.3389/fncel.2022.786926 120 MaioliniM.GauseS.TaylorJ.SteakinT.ShippG.LamichhaneP.et al (2020)

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