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On the selectivity of superoxide dismutase mimetics and its importance in pharmacological studies

Further, it was observed that the inhibition of glutaminolysis suppressed mTORC1 activity, by evaluating pS6 levels in the glutamine-dependent RERF-LC-AI cell line but the activity of mTORC1 was not affected in the QG56 glutamine-independent cell line

10.1007/s40262-023-01275-x 43 Ten BrinkM

Cell 1997

Understanding this pathway is not only key to elucidating the origin of SFN but also provides the essential toolkit for its sustainable enhancement through genetic biofortification