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Modulation of specific subpopulations of reactive astrocytes may help reduce their harmful effects without compromising their beneficial functions

The pattern suggests that each additional receptor target provides incremental but meaningful improvements

It also phosphorylates SREBP-1c at Ser372, which inhibits proteolytic maturation, nuclear translocation of SREBP-1c and the expression of downstream fatty acid synthase gene, thus increasing fatty acid -oxidation and reducing de novo synthesis of TG (25) to prevent hepatocyte steatosis by reducing the accumulation of TG in HepG2 cells (26)

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The primary function of the BBB is to protect the brain from pathogens, toxins, and any other harmful substances or fluctuations in the blood