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Neutrophil extracellular traps (NETs), composed of chromatin, granular proteins, and histones, are released during infections to trap and neutralize pathogens

Documented improvements in OA and joint pains associated with sulfurated water hydrotherapy, many times accompanied by the simultaneous ingestion of such waters has also been related to the GSH involvement in the antioxidant cascade

doi: 10.3389/fonc.2023.1256769 8 Della ChiesaMCarlomagnoSFrumentoGBalsamoMCantoniCConteRet al

Depo Yang, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

However, this is rather questionable since there is accumulating evidence of triggering/induction of BP by this treatment which may be related to a relative increase in IL-4 and IL-13 levels following IL-31 inhibition [151]