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Calcitonin gene-related peptide increases during migraine attacks and is an important contributor to vascular dilation and nerve inflammation

That imaging tells me whether we're dealing with active degeneration, scar tissue, partial tearing, or a healing response that stalled

A phase 2 randomised controlled trial published in the New England Journal of Medicine (2023) reported substantial weight loss and improvements in glycaemic parameters, though the trial was conducted in a closely monitored clinical setting with defined eligibility criteria

10.1038/nrrheum.2013.160 217 RisbudM

Never start, stop, or change a medication without talking to a licensed provider