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BloemenOde KoningMSchmitzNNiemanDBeckerHEde HaanLet al

Indeed, in both studies, the highest frequency of TEAEs was in the normal function groups, possibly owing to the smaller sample sizes in the more severe impairment groups, or alternatively because participants with more serious health concerns, such as those with severe renal or hepatic impairment, may be less likely to notice or report mild or moderate TEAEs, as observed in populations with cancer [21]

doi: 10.1002/alz.13844, 214

Some other studies, however, have failed to find reductions in either L-carnitine or acetylcarnitine

a 100 mm visual analogue scale (VAS) was used to assess pain