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As the primary barrier to environmental and metabolic stress, the skin is susceptible to oxidative damage

Ethanol is oxidized to acetaldehyde by alcohol dehydrogenase I (ADH1), catalase (CAT) and/or cytochrome P450 2E1 (CYP2E1)

However, it is essential to note that GSH levels in both dose groups generally returned to baseline levels after a one-month washout period, suggesting that continuous supplementation is necessary to maintain elevated GSH levels

O 2 may prematurely take up electrons from the ETC during this process, producing a small amount of O 2 -

Liz MA, Coelho T, Bellotti V et al (2020) A narrative review of the role of transthyretin in health and disease