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458 Similarly, EVs loaded with small interfering RNAs targeting the FGFR3-TACC3 fusion gene effectively inhibited tumor cell viability while sparing adjacent normal tissues, demonstrating precision in gene-targeted therapy

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Levodopas long-term efficacy is, on the other hand, compromised by the development of response oscillations and drug-induced dyskinesias in a majority of patients due to the progressive degeneration of dopaminergic neurons and pulsatile administration of levodopa, and these limitations are the main reasons for continued efforts towards improvements of current dopaminergic strategies

Mller-Schssele SJ, Wang R, Gtle DD, Romer J, Rodriguez-Franco M, Scholz M, Buchert F, Lth VM, Kopriva S, Drmann P, Schwarzlnder M, Reski R, Hippler M, Meyer AJ (2020) Chloroplasts require glutathione reductase to balance reactive oxygen species and maintain efficient photosynthesis

Takeshita T, Ota S, Yamazaki T, Hirata A, Zachleder V, Kawano S