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Aldo-eto reductase family 1 member B10 inhibitors: Potential drugs for cancer treatment

[DOI] [PubMed] [Google Scholar] 54.Anderson CP, Tsai JM, Meek WE, et al

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Selumetinib, a MEK inhibitor, has shown promising results in clinical trials for treating NF1 patients with PN and was approved by the US Food and Drug Administration in April 2020 for pediatric NF1 patients aged at least 2 years who have symptomatic and inoperable PN

These discoveries have implications for treating particular diseases such as neurodegeneration and cancer, as well as general anti-aging efforts