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has received funding support from Hoffman-La Roche, Ferring Pharmaceuticals and NovImmune and during the past 5 years has acted as an advisory consultant for Roche, Chugai Pharmaceuticals, NovImmune, Genentech, Sanofi Regeneron, Johnson & Johnson, Janssen Pharmaceuticals, Eleven Biotherapeutics and UCB

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428 PDK4 deficiency enhances hepatic glycolysis by increasing the GCK level and improving insulin sensitivity during liver regeneration