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485 Primary Prevention: Emerging Evidence Clinical trials and observational studies are also examining the potential role of colchicine in primary prevention of thrombotic events (ie, in people who have never had a cardiovascular emergency or known chronic coronary artery disease)

doi: 10.1016/j.cmet.2023.06.013 125 WangSZhengYYangFZhuLZhuXQWangZFet al

The liver is an insulin-sensitive organ and like skeletal muscle, is responsible for glucose disposal via glycogen synthesis

Genetics plays a role here, and people who have genetically lower IgE levels are less likely to have chronic urticaria.[ref] Mast cells, atrial fibrillation, and cardiac diseases: Researchers estimate that there are ~50,000 mast cells/g of human heart tissue

These are standard hepatoprotection outcome measures across I/R, CCl, and APAP (acetaminophen overdose) injury paradigms