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10.1038/416552a 77

Research has examined its effects on incisional wounds, excisional wounds, burns, diabetic ulcers, and various types of fistulas

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For instance, using a series of inducible and tissue-specific transgenic constructs with a bacterially-derived enzyme -- methioninase, which degrades methionine to ammonia, -ketobutyrate, and methanthiol -- to reduce in vivo methionine, Parkhitko and others found that they could both investigate the consequences of whole body and tissue-specific reduced methionine levels ( Branched-chain amino acids A group of three other essential amino acids, the branched-chain amino acids (BCAAs) leucine, isoleucine, and valine, have also drawn interest due to their known impact on protein synthesis, food intake, and metabolic health (Vellai et al., 2003