chloroquine glutathione synthase

chloroquine glutathione synthase Scheme of proposed mode of action of and amodiaquine Glutathione Synthetase - an overview

Name: chloroquine glutathione synthase Scheme of proposed mode of action of and amodiaquine Glutathione Synthetase - an overview
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Glutathione Synthetase an overview ScienceDirect Topics Organelle specific localization of glutathione in plants grown under different light intensities and spectra Histochemistry and Cell Biology Springer Nature Link Modelling changes in glutathione homeostasis as a function of quinone redox metabolism Scientific Reports Leveraging the effects of chloroquine on resistant malaria parasites for combination therapies BMC Bioinformatics Springer Nature Link Mutagenic, Genotoxic and Immunomodulatory effects of Hydroxychloroquine and Chloroquine: a review to evaluate its potential to use as a prophylactic drug against COVID 19 Genes and Environment Springer Nature Link

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Science 312 , 13551359 (2006)

chloroquine glutathione synthase Scheme of proposed mode of action of and amodiaquine Glutathione Synthetase - an overview

Yes this is arguably where the strongest scientific backing exists

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Notably, the upregulated metabolites were related primarily to glutathione metabolism, including key precursors for glutathione synthesis ( -glutamylcysteine and acetylcysteine), metabolites involved in glutathione catabolism and its byproducts (cysteinylglycine and Cys-Gly), and both oxidized and reduced forms of glutathione (GSSG and GSH) and glutathione disulfide