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These hepatocytes were plated onto 6-well or 12-well plates that had been pre-coated with collagen

Furthermore, pyruvate dehydrogenase complex can translocate from the mitochondria to the nucleus (in a manner still unclear) during cell-cycle progression, generating a nuclear pool of acetyl-CoA from pyruvate and increasing the acetylation of core histones important for S phase entry as well as expression of damage-response genes among others (82

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Designed to promote cellular energy metabolism, microbial balance, and pathways associated with healthy aging

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