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Rats with acute liver failure were injected with 1x10 7 cells /kg BMSCs and BMSCs-33 via the tail veins, respectively

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Despite significant advances in mechanical treatments such as rotational atherectomy, these methods are passive treatments for advanced calcification (191)

Remarkably, KDS12025 demonstrated significant efficacy in mitigating RA pathology, as evidenced by a reduction in the CIA score, a clinical measure of joint inflammation severity, and improvements in histological parameters, including synovial hyperplasia and cartilage destruction, as shown via H&E and toluidine blue staining (Supplementary Fig